Jesse Weber Live is a weeknight live news program on NewsNation, the cable network owned by Nexstar Media Group, airing at 11 p.m. Eastern. It is hosted by Jesse Weber, the network's chief legal analyst, and the network describes it as a fast-paced take on the day's headlines seen "through the lens of legal expertise." Unidentified anomalous phenomena are a recurring strand of the show, though a minority of its segments.

NewsNation announced the hour on December 17, 2025, as part of an expansion of its live programming, saying Weber would unpack the day's major developments with a focus on legal affairs, preview the next day's stories and welcome a featured guest each night. The show debuted on January 19, 2026, the same night as Katie Pavlich Tonight at 10 p.m., completing a weeknight lineup that runs from Elizabeth Vargas at 7 p.m. through Chris Cuomo and Leland Vittert. Weber, who joined the network in March 2023 as a legal contributor and guest anchor, continues as its legal analyst.

Most of the program's airtime goes to crime, courts and breaking news. Its 2026 segments covered the death of teenager Anna Kepner on a cruise ship, the murder trial and sentencing of former "American Idol" contestant Caleb Flynn, the Cornell University sexual assault case, the disputed U.S. death toll in the war with Iran, and recurring body-language analysis of defendants and public figures with behavior analyst Scott Rouse.

The UAP segments began early. In March 2026 former Air Force officer Robert Salas described his claim that UFOs disabled nuclear missiles in 1967, and in April the show covered the disappearance of Steven Garcia within the wider story of missing and deceased scientists. After the first Pentagon release of UAP files in May, Weber convened a panel with "UFO Witness" host Ben Hansen, who rated it eight out of ten, former astronaut Terry Hart and the Disclosure Foundation's Jordan Flowers. Harvard astrophysicist Avi Loeb became the most frequent guest: he suggested that orbs in the June files might be "very sophisticated Chinese drones," said the August tranche held "not enough data" to infer what the objects were, and in October denied a report that he had predicted alien contact within 16 days. Former UAP task force analyst Sarah Gamm reviewed the sixth release in September. In May the show also aired an interview with the parents of Chandra Levy, who said they believed their daughter's 2001 murder might be connected to UFO knowledge.

Jesse Weber Live treats the subject as one running story among many rather than as its specialty. Its UAP coverage in 2026 relied on scientists, former officials and witnesses responding to each official file release, giving the late-night hour a steady place in NewsNation's broader coverage of the disclosure debate.